(R)-(+)-2-Chloropropionic acid
(R)-(+)-2-Chloropropionic acid
CAS: 7474-05-7
Molecular Formula: C3H5ClO2
(R)-(+)-2-Chloropropionic acid - Names and Identifiers
| Name | (R)-(+)-2-Chloropropionic acid |
| Synonyms | (2R)-2-chloropropanoate R-2-chloro-propionic acid (2R)-2-chloropropanoic acid (R)-(+)-2-Chloropropionic Acid (R)-(+)-2-Chloropropionic acid (2R)-(+)-2-Chloropropanoic acid (R)-(+)-2-CHLOROPROPIONIC ACID FOR SYNTH |
| CAS | 7474-05-7 |
| EINECS | 626-432-5 |
| InChI | InChI=1/C3H5ClO2/c1-2(4)3(5)6/h2H,1H3,(H,5,6)/t2-/m1/s1 |
(R)-(+)-2-Chloropropionic acid - Physico-chemical Properties
| Molecular Formula | C3H5ClO2 |
| Molar Mass | 108.52 |
| Density | 1.258 g/mL at 20 °C (lit.) |
| Melting Point | -12°C |
| Boling Point | 185-188 °C (lit.) |
| Specific Rotation(α) | 14 º (neat) |
| Flash Point | 140°F |
| Vapor Presure | 0.26mmHg at 25°C |
| Appearance | clear liquid |
| Color | Colorless to Almost colorless |
| BRN | 1720258 |
| pKa | 2.96±0.10(Predicted) |
| Storage Condition | −20°C |
| Refractive Index | n20/D 1.4345(lit.) |
(R)-(+)-2-Chloropropionic acid - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R22 - Harmful if swallowed R35 - Causes severe burns |
| Safety Description | S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2511 8/PG 3 |
| WGK Germany | 3 |
| HS Code | 29159000 |
| Hazard Class | 8 |
| Packing Group | III |
(R)-(+)-2-Chloropropionic acid - Introduction
(R)-( )-2-Chloropropionic acid is an organic compound with the chemical formula C3H5ClO2 and the structural formula CH3CH(Cl)COOH. The following is a description of its nature, use, preparation and safety information:
Nature:
- (R)-( )-2-Chloropropionic acid is a colorless to slightly yellow liquid that can be volatilized at room temperature. It has a pungent odor and is soluble in water and organic solvents such as ethanol and acetic acid.
Use:
- (R)-( )-2-Chloropropionic acid is mainly used as an important intermediate in organic synthesis. It can be used in the manufacture of pharmaceuticals, pesticides and other organic compounds, such as amines, esters and amides.
Preparation Method:
- (R)-( )-2-Chloropropionic acid can be prepared:
1. Acrylic acid is reacted with sodium hypochlorite (NaClO) or cuprous chloride (CuCl) to obtain (R)-( )-2-chloropropionitrile;
2. (R)-( )-2-chloropropionitrile is reacted with water to hydrolyze to generate (R)-( )-2-Chloropropionic acid.
Safety Information:
- (R)-( )-2-Chloropropionic acid is an irritant substance, avoid contact with skin and eyes.
-Wear appropriate protective gloves, safety glasses and protective clothing during use and handling.
-Do not inhale the vapors of the compound. If inhaled, move to fresh air immediately.
-If ingestion or accidental entry into the eye, seek medical attention immediately and provide the packaging or label to the doctor.
Nature:
- (R)-( )-2-Chloropropionic acid is a colorless to slightly yellow liquid that can be volatilized at room temperature. It has a pungent odor and is soluble in water and organic solvents such as ethanol and acetic acid.
Use:
- (R)-( )-2-Chloropropionic acid is mainly used as an important intermediate in organic synthesis. It can be used in the manufacture of pharmaceuticals, pesticides and other organic compounds, such as amines, esters and amides.
Preparation Method:
- (R)-( )-2-Chloropropionic acid can be prepared:
1. Acrylic acid is reacted with sodium hypochlorite (NaClO) or cuprous chloride (CuCl) to obtain (R)-( )-2-chloropropionitrile;
2. (R)-( )-2-chloropropionitrile is reacted with water to hydrolyze to generate (R)-( )-2-Chloropropionic acid.
Safety Information:
- (R)-( )-2-Chloropropionic acid is an irritant substance, avoid contact with skin and eyes.
-Wear appropriate protective gloves, safety glasses and protective clothing during use and handling.
-Do not inhale the vapors of the compound. If inhaled, move to fresh air immediately.
-If ingestion or accidental entry into the eye, seek medical attention immediately and provide the packaging or label to the doctor.
Last Update：2024-04-09 02:00:48
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